Sunday, January 1, 2012

Research webpage

Dr. Colinet Hervé
Université de Rennes 1
263 AVE du Général Leclerc
CS 74205
35042 Rennes Cedex
tél : +33 (0)2 23 23 64 38

Email :

Research theme

My research focuses on adaptive responses of ectotherms to environmental and anthropic constraints. I have a special interest in adaptation to thermal stress in arthropods (e.g. Drosophila flies). I use various approaches, ranging from ecophysiology to evolutionary and molecular biology, in order to gain an integrated and multi-scale understanding of stress adaptation from genes to individual responses.

Current Project

Link to Suzukill website below


Education & Professional record

Sept. 2002 : Agricultural Bioengineer, University of Louvain
Dec. 2007 : Ph.D. in Agricultural Bioengineering, University of Louvain
June 2019 : Habilitation (HDR), University of Rennes 1


2002-2003 : Research assisant (convention RW), University of Louvain
2003-2007 : Research assisant (convention FIRST-Europe Objectif 3), University of Louvain
2008-2010 : Postdoc researcher, Fonds de la Recherche Scientifique (FNRS)
2012-2013 : Temporary whole-time Lecturer, University of Rennes 1
From 2013 : Permanent CNRS researcher (CR1), University of Rennes 1

  • 2004-2007 : Six stays of two months. Lab of Dr Philippe Vernon, SBP Paimpont, UMR 6553 CNRS, France.
  • 2006 : A two months stay. Lab of Prof. Conrad Cloutier, University of Laval, Québec, Canada.
  • 2009-2010 : Post-doctoral stay of 18 months. Lab of Prof. Ary Hoffmann, University of Melbourne, Australia.
  • 2010-2012 : Post-doctoral stay of 22 months. Lab of Dr David Renault, UMR 6553, University of Rennes 1, France.

Editorial responsibilities for Journals
  • Member of the Editorial board of The Canadian Entomologist     (link here)

 Head of the Analytical platform PLAY (ECOBIO) (link here)

Publications         (Reprints available, just ask me by email)

Links to the papers click here
  • Legrand, M.A., Colinet, H., Vernon, P., Hance, T. 2004. Autumn, winter and spring dynamics of aphid Sitobion avenae and parasitoid Aphidius rhopalosiphi interactions. Annals of Applied Biology. 145: 139-144.     Pdf 
  • Colinet, H., Salin, S., Boivin, G., Hance, T. 2005. Host age and fitness-related traits in a koinobiont aphid parasitoïde. Ecological Entomology. 30: 473-479.     Pdf
  • Colinet, H., Hance, T., Vernon, P. 2006. Water relations, fat reserves, survival, and longevity of a cold-exposed parasitic wasp Aphidius colemani (Hymenoptera: Aphidiinae). Environmental Entomology 35: 228-236.     Pdf
  • Colinet, H., Renault, D., Hance, T., Vernon, P. 2006. The impact of fluctuating thermal regimes on the survival of a cold-exposed parasitic wasp, Aphidius colemani. Physiological Entomology 31: 234-240.     Pdf
  • Colinet, H., Vernon, P., Hance, T. 2007. Does thermal-related plasticity in size and fat reserves influence supercooling abilities and cold-tolerance in Aphidius colemani (Hymenoptera: Aphidiinae) mummies? Journal of Thermal Biology. 32: 374-382.    Pdf
  • Colinet, H., Hance, T., Vernon, P., Bouchereau, A., Renault, D. 2007. Does fluctuating thermal regime trigger free amino acid production in the parasitic wasp Aphidius colemani (Hymenoptera: Aphidiinae)? Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 147: 484-492.     Pdf
  • Colinet, H., Boivin, G., Hance, T. 2007. Manipulation of parasitoid size using temperature-size rule: fitness consequences. Oecologia. 152: 425-433.     Pdf
  • Lalouette, L., Koštál, V., Colinet, H., Gagneul, D., Renault, D. 2007. Cold-exposure and associated metabolic changes in adult tropical beetles exposed to fluctuating thermal regimes. European Journal of Biochemistry (The FEBS Journal). 274: 1759-1767.     Pdf
  • Colinet, H., Nguyen, T.T.A., Cloutier, C., Michaud, D., Hance, T. 2007. Proteomic profiling of a parasitic wasp exposed to constant and fluctuating cold exposure. Insect Biochemistry and Molecular Biology. 37: 1177-1188.     Pdf
  • Colinet, H. Hance, Th. 2009. Male reproductive potential of Aphidius colemani (Hymenoptera: Aphidiinae) exposed to constant or fluctuating thermal regimes. Environmental Entomoloy. 38: 242-249.     Pdf
  • Colinet H. & Th. Hance. 2010. Inter-specific variation in the response to low temperature storage in different aphid parasitoids. Annals of Applied Biology. 156: 147–156.     Pdf
  • Colinet, H., Lee S.F., Hoffmann, A. 2010. Temporal expression of heat shock genes during cold stress and recovery from chill coma in adult D. melanogaster. FEBS Journal 277: 174-185.     Pdf
  • Colinet, H., Hoffmann, A. 2010. Gene and protein expression of Drosophila Starvin during cold stress and recovery from chill coma. Insect Biochemistry and Molecular Biology. 40: 425-428.     Pdf
  • Colinet, H., Lee S.F., Hoffmann, A. 2010. Functional characterization of the Frost Gene in Drosophila melanogaster: Importance for Recovery from Chill Coma. PLoS ONE 5(6): e10925.     Pdf
  • Colinet, H., Muratori, F., Hance, T. 2010. Cold-induced expression of diapause in Praon volucre: fitness cost and morpho-physiological characterization. Physiological Entomology. 35: 301-307.     Pdf
  • Colinet, H., Lee S.F., Hoffmann, A. 2010. Knocking down expression of Hsp22 and Hsp23 by RNA interference affects recovery from chill coma in Drosophila melanogaster. Journal of Experimental Biology. 213: 4146-4150.     Pdf
  • Colinet, H., Boivin, G. 2011. Insect parasitoids cold storage: a comprehensive review of factors of variability and consequences. Biological Control. 58 : 83-95.     Pdf
  • Colinet, H. 2011. Disruption of ATP homeostasis during chronic cold stress and recovery in the chill susceptible beeltle (Alphitobius diaperinus). Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology. 160: 63–67.     Pdf
  • Colinet, H., Lalouette, L., Renault, D. 2011. A model for time-temperature-mortality relationship in the chill-susceptible beetle, Alphitobius diaperinus, exposed to fluctuating thermal regimes. Journal of thermal Biology. 36: 403-408.     Pdf
  • Colinet, H., Hoffmann, A. 2012. Comparing phenotypic effects and molecular correlates of developmental, gradual and rapid cold acclimation responses in Drosophila melanogaster. Functional Ecology. 26: 84-93.     Pdf
  • Colinet, H., Larvor, V., Laparie, M., Renault, D. 2012. Exploring the plastic response to acclimation through metabolomics. Functional Ecology. 26 : 711–722.     Pdf
  • Colinet, H., Renault, D., Guével, B., Com, E. 2012. Metabolic and proteomic profiling of diapause in the aphid parasitoid Praon volucre. PLoS ONE 7(2): e32606.     Pdf
  • Teets, N.M., Peyton, J.T., Ragland, G. J., Colinet, H., Renault, D., Hahn, D.A., Denlinger, D.L. 2012. Combined transcriptomic and metabolomic approach uncovers molecular mechanisms of cold tolerance in a temperate flesh fly. Physiological Genomics. 44:764-77.     Pdf
  • Colinet, H., & Renault, D. 2012. Metabolic effects of CO2 anaesthesia in Drosophila melanogaster. Biology Letters. 8: 1050-1054.     Pdf
  • Teets, N.M., Peyton, J.T., Colinet, H., Renault, D., Kelley, J.L., Kawarasaki, Y., Lee, Jr., R.E., Denlinger, D.L. 2012. Gene expression changes governing extreme dehydration tolerance in an Antarctic insect. Proceedings of the National Academy of Sciences. 109 (50) 20744-20749. Pdf
  • Colinet, H., Larvor, V., Bical, R., Renault, D. 2013. Dietary sugars affect cold tolerance of Drosophila melanogaster. Metabolomics. 9 : 608-622.     Pdf
  • Colinet, H., Siaussat, D., Bozzolan, F., Bowler, K. 2013. Rapid decline of cold tolerance at young age is associated with expression of stress genes in Drosophila melanogaster. Journal of Experimental Biology. 216: 253-259.     Pdf
  • Foray, V., Desouhant, E., Voituron, Y., Larvor,V., Renault, D., Colinet, H., Gibert,P. 2013. Does cold tolerance plasticity correlate with the thermal environment and metabolic profiles of a parasitoid wasp? Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology. 164: 77-83.     Pdf
  • Colinet, H., Overgaard, J., Com, E., Sørensen, J.G. 2013. Proteomic profiling of thermal acclimation in Drosophila melanogaster. Insect Biochemistry and Molecular Biology.  43: 352-365.     Pdf
  • Khodayari, S., Colinet, H., Moharramipour, S., Renault, D. 2013. Seasonal Change in the Cold Hardiness of the Two-Spotted Spider Mite Females (Acari: Tetranychidae) - Environmental Entomology. 42: 1415-1421.     Pdf  
  • Colinet, H.,Renault, D. 2014. Dietary live yeast alters metabolic profiles, protein biosynthesis and thermal stress tolerance of Drosophila melanogaster. Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology.  170: 6-14.     Pdf
  • Overgaard, J., Sørensen, J.G., Com, E., Colinet, H. 2014. The rapid cold hardening response of Drosophila melanogaster: Complex regulation across different levels of biological organization. Journal of Insect Physiology. 62: 46-53.     Pdf  
  • Colinet, H., Sinclair, B.J., Vernon, P., Renault, D. 2015. Insects in Fluctuating Thermal Environments. Annual Review of Entomology 60: 123-140.     Pdf
  • Renault D., Henry Y., Colinet H. 2015. Acclimation to desiccating conditions and cross-tolerance with thermal stress in the lesser mealworm Alphitobius diaperinus (coleoptera: tenebrionidae). Revue d’Ecologie. Sup 12 « Espèces invasives » 70: 33-41      Pdf
  • Le Bourg, E., Gauthier, T., Colinet, H. 2015. Feeding on frozen live yeast has some deleterious effects in Drosophila melanogaster. Experimental Gerontology. 69: 202-210     Pdf
  • Colinet, H., Chertemps, T.,  Boulogne, I., Siaussat, D. 2015. Age-related decline of abiotic stress tolerance in young Drosophila melanogaster adults. Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences, 71: 1574-1580.    Pdf
  • Koštál, V., Korbelova, J., Stetina, T., Poupardin, R., Colinet, H., Zahradnickova, H., Opekarova, I., Moos, M., Šimek, P. 2016. Physiological basis for low-temperature survival and storage of quiescent larvae of the fruit fly Drosophila melanogaster. Scientific Reports 6:32346.   Pdf
  • Colinet, H., Renault, D., Javal, M.,Berková, P., Šimek, P., Koštál, V. 2016. Uncovering the benefits of fluctuating thermal regimes on cold tolerance of drosophila flies by combined metabolomic and lipidomic approach. BBA - Molecular and Cell Biology of Lipids. 1861: 1736-1745.    Pdf
  • Javal, M., Renault, D., Colinet, H. 2016. Impact of fluctuating thermal regimes on Drosophila melanogaster survival to cold stress. Animal Biology. 66: 427-444.  Pdf
  • Colinet, H., Renault, D., Roussel, D. 2017. Cold acclimation allows Drosophila flies to maintain mitochondrial functioning under cold stress. Insect Biochemistry and Molecular Biology. 80: 52-60.     Pdf
  • Henry, Y., Piscart, C., Charles, S., Colinet, H. 2017. Combined effect of temperature and ammonia on survival and molecular response of the freshwater crustacean Gammarus pulex/ Ecotoxicology and Environmental Safety. 137: 42-48.   Pdf
  • Enriquez, T & Colinet, H. 2017. Basal tolerance to heat and cold exposure of the spotted wing drosophila, Drosophila suzukii. Peer Journal. 5:e3112.       Pdf
  • Colinet, H., Pineau, C., Com, E. 2017. Large scale phosphoprotein profiling to explore Drosophila cold acclimation regulatory mechanisms. Scientific Reports 7:1713.     Pdf
  • Colinet, H. Renault. D. 2018. Post-stress metabolic trajectories in young and old flies. Experimental Gerontology. 102: 43-50.    Pdf
  • Nikolouli K., Colinet, H., Renault, D., Enriquez, T., Mouton, L., Gibert, P., Sassu, F., Caceres, C., Stauffer, C.,Cardos o-Pereira, R., Bourtzis, K. 2018. Sterile insect technique and Wolbachia symbiosis as potential tools for the control of the invasive species Drosophila suzukii. Journal of Pest Science. 91: 489-503    Pdf
  • Henry, Y., Renault, D., Colinet, H. 2018. Hormesis-like effect of mild larval crowding on thermotolerance in Drosophila flies. Journal of Experimental Biology. doi: 10.1242/jeb.169342    Pdf
  • Heys, C., Lizé, A., Colinet, H., Price, T., Prescott, M., Ingleby, F., Lewis, Z. 2018. Evidence that the microbiota counteracts male outbreeding strategy by inhibiting sexual signaling in females. Frontiers in Ecology and Evolution. 6:29.    Pdf
  • Colinet, H., Rinehart, J., Yocum, G., Greenlee, K. 2018. Mechanisms underpinning the beneficial effects of fluctuating thermal regimes in insect cold tolerance.  Journal of Experimental Biology. 221, jeb164806. doi:10.1242/jeb.164806   Pdf
  • Enriquez, T., Ruel, D., Charrier, M., Colinet, H. 2018. Effects of fluctuating thermal regimes on cold survival and life history of the spotted wing Drosophila (Drosophila suzukii, Matsumara). Insect Science (DOI 10.1111/1744-7917.12649).   Pdf
  • Henry, Y. & Colinet, H. 2018.Microbiota disruption leads to reduced cold tolerance in Drosophila flies. Science of Nature. 105:59.   Pdf
  • Enriquez, T., Renault, D., Charrier, M., Colinet, H. 2018. Cold acclimation favors metabolic stability in Drosophila suzukii.  Frontiers in Physiology. 9:1506.   Pdf 
  • Clayre Grumiaux, C., Andersen, M.K., Colinet, H., Overgaard, J. 2019. Fluctuating thermal regime preserves physiological homeostasis and reproductive capacity in Drosophila suzukii. Journal of Insect Physiology. 113: 33-41.    Pdf
  • Enriquez, T. & Colinet, H. 2019. Cold acclimation triggers lipidomic and metabolic adjustments in the spotted wing drosophila Drosophila suzukii (Matsumara). American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 316: R751–R763 
  • Enriquez T., Colinet H. 2019. Cold acclimation triggers major transcriptional changes in Drosophila suzukii.  BMC Genomics. 20:413   Pdf


Colloque d'Ecophysiologie Animale, 4ème édition will take place in Rennes in October 2019. 

Organized by H.COLINET & D. RENAULT 




International Symposium of Environmental Physiology on Ectotherms and Plants (ISEPEP9) will take place in Rennes in July 2021.

Organized by H.COLINET & D. RENAULT